UNGUIDED
CDK20: FL 2280mm,  F/4.5,  0.34 arcsec/pixel raw
Moon:   60%

My comparison image shows clearly that James Webb Space Telescope images include galaxy images in the Infared wavelengths that do not appear in ground based images.
You will find about 17 galaxies visible in my comparison image, and far more in the Hubble image.
However, there are about 6 or 7 in the Hubble image that should show in the CDK20 image based on their intensity, but do not show whatsover.
An example is the second galaxy down on the right side, which is quite bright in the Hubble image, but not present in the CDK20 image, while much dimmer galaxies, close enough to not require infrared, do show.

This image from NASA is the first ever published image taken by the James Webb Space Telescope with the 18 hexagonal primary mirror segments fully aligned.  The precision and detail of this image are breathtaking, foretelling the amazing images that will follow.

NASA's image:
An image of the star 2MASS J17554042+6551277 taken by the James Webb Space Telescope that confirmed the performance of the spacecraft's optics. The rays are diffraction patterns from the shape of the mirror segments.

From NASA:
NASA announced March 16 that spacecraft team had finished the “coarse phasing” and “fine phasing” steps of alignment of the telescope’s optics. Those steps involved very small changes in the positions of JWST’s 18 primary mirror segments such that their images were aligned on top of each other and then matched to within a wavelength of infrared light.The completion of the fine phasing means that the telescope is now fully aligned for one of its main instruments, the Near-Infrared Camera, and that there are no flaws like the spherical aberration in the primary mirror of the Hubble Space Telescope that diminished its performance after launch until corrective optics were installed.

=======FINAL Image========
My image of the same star uses the same FOV as the JWST NIRCam alignment image.
In addition to the bright central star, my image shows 'something' for 12 of the very small, likely galaxies that appear in great detail in the JWST image.  And my image presents the bright central star enormously bloated in comparison.

The JWST image is taken with the NIRCam camera.
The FOV of this first published image is 2.9' x 1.8' arcminutes.

NIRCam/JWST specs:
Mirror Diameter:  6.5 meters
Focal Length:        131 meters
Focal Ratio:            f/20.2
Field of View:     4.4' x2.2' arcminutes
Sensor Pixels:    4096 x 2048 pixels ( 2 each 2048 x 2048 )
Pixel Size:           42 microns square ( 125 times area of ASI6200mm pixels )
Sensor Size:       170 mm x 85 mm
Resolution:        0.064 arcseconds/pixel  ( CDK20 resolution / 5.3 )

=======ORIGINAL Image ========
My full sized original image FOV:  49' x 40' minutes.
It is rotated 8.5 degrees clockwise to line up with the JWST image.
Image center ....... RA: 17 55 40.301 Dec: +65 51 28.20
Star:  2MASS J17554042+6551277
The bright alignment star is in the exact center of the image.

The James Webb Space Telescope (JWST) is a space telescope designed to conduct infrared astronomy. As the largest telescope in space, it is equipped with high-resolution and high-sensitivity instruments, allowing it to view objects too old, distant, or faint for the Hubble Space Telescope.[9] This enables investigations across many fields of astronomy and cosmology, such as observation of the first stars and the formation of the first galaxies, and detailed atmospheric characterization of potentially habitable exoplanets.[10][11][12]

Although the Webb's mirror diameter is 2.7 times larger than that of the Hubble Space Telescope, it produces images of comparable sharpness because it observes in the longer-wavelength infrared spectrum. The longer the wavelength of the spectrum, the larger the information-gathering surface required (mirrors in the infrared spectrum or antenna area in the millimeter and radio ranges) for an image comparable in clarity to the visible spectrum of the Hubble Space Telescope.

The Webb was launched on 25 December 2021 on an Ariane 5 rocket from Kourou, French Guiana. In January 2022 it arrived at its destination, a solar orbit near the Sun–Earth L2 Lagrange point, about 1.5 million kilometers (930,000 mi) from Earth. The telescope's first image was released to the public on 11 July 2022.

My Collections:
Abell Planetary Nebulae (Complete)
Galaxies
Messier Objects
Planetary Nebulae
Sharpless 2 Objects